報告承辦單位:物理與電子科學學院 報告內容:Shaping Sound Waves for Advanced Acoustic Tweezers: From Fundamentals to Biomedical Applications 報告人姓名:蔡飛燕 報告人所在單位:中國科學院深圳先進技術研究院 報告人職稱/職務及學術頭銜:研究員、深圳市杰青 報告時間:2025年6月26日 上午9:30 報告地點:理科樓B413 |
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報告人簡介: 蔡飛燕,中國科學院深圳先進技術研究院研究員,博士生導師,深圳市杰青。2008年獲武漢大學凝聚態物理博士學位;同年加入深圳先進技術研究院生物醫學與健康工程研究所工作,歷任助理研究員,副研究員,研究員;2019-2020年美國密西西比大學國家物理聲學中心任訪問學者。迄今已主持國家自然科學基金4項,科技部重點研發計劃子課題2項,深圳市重點項目2項;在JASA、Physical Review系列、Nature系列等發表論文70余篇,引用3300余次,相關工作獲美國物理學會“物理精選”和“編輯推薦”報道,H指數30;授權中國發明專利30余項,美國發明專利2項;獲得2017年國家技術發明二等獎(2/6),2019年深圳市自然科學一等獎(3/5)。目前主要的研究方向為聲鑷理論、技術及其在生物醫學工程中的應用。 |
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報告摘要: Optical tweezers, recognized with the 2018 Nobel Prize in Physics, have showcased exceptional capabilities in manipulating micro- and nanoparticles. In comparison, acoustic tweezers provide stronger radiation forces, greater penetration depth, and reduced thermal damage, making them particularly suitable for biological applications, especially in vivo. Nonetheless, traditional acoustic tweezers face several challenges such as long wavelengths, diffraction limits, and rigid designs, limiting their precision and broader application in biomedicine. In this presentation, I will share our advancements in shaping sound waves for advanced acoustic tweezers and address these challenges. First, we designed localized gradient acoustic field to create a precise platform for high-throughput cellular manipulation. Second, we developed 3D acoustic tweezers to enable multidimensional manipulation in complex environments. Third, we innovated structured resonant fields to facilitate controllable trapping and releasing, laying the groundwork for targeted drug delivery near vascular stents. Finally, I will prospect ultrasound-assisted drug delivery, both in vivo and in vitro, and explore the future development of on-demand acoustic tweezer technologies tailored for practical medical applications. |